Systematic Review of Economic Evaluation Studies of Stroke Disease: Cost Effectiveness

Nuzulia Farah Ardhila; Dwi Endarti; Tuangrat Phodha

doi:10.30595/jhepr.v2i1.110

Authors

Nuzulia Farah Ardhila Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia
Dwi Endarti Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia
Tuangrat Phodha Faculty of Pharmacy, Thammasat University, Rangsit Campus, Pathum Thani, Thailand

DOI:

https://doi.org/10.30595/jhepr.v2i1.110

Keywords:

pharmacoeconomic, ischemic stroke, cost-effectiveness, telestroke, strokecare.

Abstract

Background: Updating pharmacoeconomics of stroke in the past 5 years from Europe, the Americas, and the Pacific Area. This ischemic stroke study relates to telestroke and stroke care. To evaluate the extent and economic quality of published ischemic stroke economic evaluation especially in telestroke and stroke care in the past 5 years.

Methods: A systematic review was conducted according to PRISMA guidelines.. The inclusion criteria for the studies were 1) original research article, 2) cost-effectiveness, 3) comparing pharmacoeconomics with QALY's result, and 4) the limitation is from the past 5 years.

Results: A total of 12 studies were included from 2018-2022. The concern of the studies is in telestroke and stroke care which come from 5 Europian, 2 Americas, and 5 Pacific Area. The mean QHES scale score was 80 ± 100. All of the studies were published in English.

Conclusion: Cost-saving the result is based on the time horizon, the base year for costing, the QALY Threshold, and the discount rate used by the authors themselves. The nationality and income country will take a few values to impact the result of studies.

References

WSO. Global Stroke Fact Sheet 2022. World Stroke Organization News (2022).

WHO. World Stroke Day 2022. World Health Organization News (2022).

WHO. Number of individuals reporting to have been diagnosed with stroke.

Whetten, J. et al. Cost-effectiveness of Access to Critical Cerebral Emergency Support Services (ACCESS): a neuro-emergent telemedicine consultation program. Journal of Medical Economics 21, 398–405 (2018).

Thayabaranathan, T. et al. Global stroke statistics 2022. International Journal of Stroke 17, 946–956 (2022).

Wikipedia. Stroke. Wikipedia The Free Encyclopedia (2020).

Kühne Escolà, J. et al. Challenges of Acute Ischemic Stroke Treatment in Orally Anticoagulated Patients via Telemedicine. JCM 10, 1956 (2021).

Escobar Cervantes, C. et al. Real-world cost-effectiveness analysis of NOACs versus VKA for stroke prevention in Spain. PLoS ONE 17, e0266658 (2022).

Ni, W., Kunz, W. G., Goyal, M., Chen, L. & Jiang, Y. Quality of life and cost consequence of delays in endovascular treatment for acute ischemic stroke in China. BMC Health Economics Review 12,.

Tsou, C. et al. Effectiveness and cost-effectiveness of TeleStroke consultations to support the care of patients who had a stroke presenting to regional emergency departments in Western Australia: an economic evaluation case study protocol. BMJ Open 11, e043836 (2021).

Lin, C.-H. et al. Quality and safety of Telemedicine in acute ischemic stroke: Early experience in Taiwan. Journal of the Formosan Medical Association 121, 314–318 (2022).

Tan, E. et al. Telestroke for acute ischaemic stroke: A systematic review of economic evaluations and a de novo cost–utility analysis for a middle income country. J Telemed Telecare 1357633X2110324 (2021) doi:10.1177/1357633X211032407.

Chen, J. et al. A Systematic Review of Mobile Stroke Unit Among Acute Stroke Patients: Time Metrics, Adverse Events, Functional Result and Cost-Effectiveness. Front. Neurol. 13, 803162 (2022).

Cadilhac, D. A. et al. Economic Evaluation Protocol and Statistical Analysis Plan for the Cost-Effectiveness of a Novel Australian Stroke Telemedicine Program; the Victorian Stroke Telemedicine (VST) program. Front. Neurol. 11, 602044 (2021).

Gao, L. et al. Telemedicine for Stroke: Quantifying the Long-Term National Costs and Health Benefits. Front. Neurol. 12, 804355 (2022).

Kim, J. et al. Cost-effectiveness of the Victorian Stroke Telemedicine program. Aust. Health Rev. 46, 294–301 (2022).

Heggie, R. et al. Mechanical thrombectomy in patients with acute ischemic stroke: A cost-effectiveness and value of implementation analysis. International Journal of Stroke 15, 881–898 (2020).

Bhattarai, N. et al. Cost-effectiveness of an enhanced Paramedic Acute Stroke Treatment Assessment (PASTA) during emergency stroke care: Economic results from a pragmatic cluster randomized trial. International Journal of Stroke 17, 282–290 (2022).

Candio, P., Violato, M., Luengo-Fernandez, R. & Leal, J. Cost-effectiveness of home-based stroke rehabilitation across Europe: A modelling study. Health Policy 126, 183–189 (2022).

Al-Senani, F. et al. A national economic and clinical model for ischemic stroke care development in Saudi Arabia: A call for change. International Journal of Stroke 14, 835–842 (2019).

Wallut, L. et al. Efficiency of telemedicine for acute stroke: a cost-effectiveness analysis from a French pilot study. Int J Technol Assess Health Care 36, 126–132 (2020).

González, D., Rodríguez- Paz, C. & Fernandez- Prieto, A. Economic impact of the first pass effect in mechanical thrombectomy for acute ischaemic stroke treatment in Spain: A cost-effectiveness analysis from the national health system perspective. BMJ Open 12, (2022).

de Souza, A. C. et al. Cost-effectiveness of mechanical thrombectomy for acute ischemic stroke in Brazil: Results from the RESILIENT trial. International Journal of Stroke 17, 855–862 (2022).

Rattanavipapong, W. et al. Economic evaluation of endovascular treatment for acute ischaemic stroke in Thailand. BMJ Open 12, e064403 (2022).

Hornby, T. G., Rafferty, M. R., Pinto, D., French, D. & Jordan, N. Cost-Effectiveness of High-intensity Training vs Conventional Therapy for Individuals With Subacute Stroke. Archives of Physical Medicine and Rehabilitation 103, S197–S204 (2022).

Li, C. et al. Applicability and cost-effectiveness of the Systolic Blood Pressure Intervention Trial (SPRINT) in the Chinese population: A cost-effectiveness modeling study. PLoS Med 18, e1003515 (2021).

Martinez, G. et al. Cost-Effectiveness Study of Initial Imaging Selection in Acute Ischemic Stroke Care. Journal of the American College of Radiology 18, 820–833 (2021).

YULIASTUTI, F., KRISTINA, S. A., ENDARTI, D. & HANDAYANI, T. M. A Systematic Review of Cost Effectiveness of Pembrolizumab Versus Standard Treatment for Metastatic Non-Small Cell Lung Cancer. IJPR 13, (2021).

Barbosa, E. et al. A systematic review of the cost-effectiveness of emergency interventions for stroke in low- and middle-income countries. African Journal of Emergency Medicine 10, S90–S94 (2020).

Grotta, J. C. et al. Prospective, Multicenter, Controlled Trial of Mobile Stroke Units. N Engl J Med 385, 971–981 (2021).

Helwig, S. A. et al. Prehospital Stroke Management Optimized by Use of Clinical Scoring vs Mobile Stroke Unit for Triage of Patients With Stroke: A Randomized Clinical Trial. JAMA Neurol 76, 1484 (2019).

Liberman, A. L., Choi, H.-J., French, D. D. & Prabhakaran, S. Is the Cost-Effectiveness of Stroke Thrombolysis Affected by Proportion of Stroke Mimics? Stroke 50, 463–468 (2019).

Ebinger, M. et al. Association Between Dispatch of Mobile Stroke Units and Functional Outcomes Among Patients With Acute Ischemic Stroke in Berlin. JAMA 325, 454 (2021).